The genome sequence of the chicken DT40 bursal lymphoma cell line

About the DT40 Genome homepage

The chicken DT40 cell line is a widely used model system in the study of multiple cellular processes due to efficient homologous gene targeting in these cells (Buerstedde and Takeda, 1991). The cell line was derived from a bursal lymphoma induced by avian leukosis virus infection (Baba et al., 1985). In this homepage a de novo assembly of the DT40 genome can be downloaded or BLAST searched. Further files with information about the DT40 genome and web links are also provided.

Manuscript

János Molnár, Ádám Póti, Orsolya Pipek, Marcin Krzystanek, Nnennaya Kanu, Charles Swanton, Gábor E. Tusnády, Zoltán Szállási, István Csabai, Dávid Szüts (2014)

The genome of the chicken DT40 bursal lymphoma cell line

G3 (Genes, Genomes, Genetics), 4, 2231-2240

[Journal] [Medline] [PDF]

References

Baba, T. W., B. P. Giroir and E. H. Humphries (1985)

Cell lines derived from avian lymphomas exhibit two distinct phenotypes.

Virology 144, 139-151.

[Journal] [Medline] [PDF]

Buerstedde, J. M., and S. Takeda (1991)

Increased ratio of targeted to random integration after transfection of chicken B cell lines.

Cell 67, 179-188.

[Journal] [Medline] [PDF]