The genome sequence of the chicken DT40 bursal lymphoma cell line
About the DT40 Genome homepage
The chicken DT40 cell line is a widely used model system in the study of multiple cellular processes due to efficient homologous gene targeting in these cells (Buerstedde and Takeda, 1991). The cell line was derived from a bursal lymphoma induced by avian leukosis virus infection (Baba et al., 1985). In this homepage a de novo assembly of the DT40 genome can be downloaded or BLAST searched. Further files with information about the DT40 genome and web links are also provided.
Manuscript
- János Molnár, Ádám Póti, Orsolya Pipek, Marcin Krzystanek, Nnennaya Kanu, Charles Swanton, Gábor E. Tusnády, Zoltán Szállási, István Csabai, Dávid Szüts (2014)
- The genome of the chicken DT40 bursal lymphoma cell line
- G3 (Genes, Genomes, Genetics), 4, 2231-2240
- [Journal] [Medline] [PDF]
References
- Baba, T. W., B. P. Giroir and E. H. Humphries (1985)
- Cell lines derived from avian lymphomas exhibit two distinct phenotypes.
- Virology 144, 139-151.
- [Journal] [Medline] [PDF]
- Buerstedde, J. M., and S. Takeda (1991)
- Increased ratio of targeted to random integration after transfection of chicken B cell lines.
- Cell 67, 179-188.
- [Journal] [Medline] [PDF]